Prevalence of AAV1 neutralizing antibodies and consequences for a clinical trial of gene transfer for advanced heart failure-Reference-Cited by-同舟云学术

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Prevalence of AAV1 neutralizing antibodies and consequences for a clinical trial of gene transfer for advanced heart failure

Published:2015-12-24 Issue:3 Volume:23 Page:313-319
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Greenberg B,Butler J,Felker G M,Ponikowski P,Voors A A,Pogoda J M,Provost R,Guerrero J,Hajjar R J,Zsebo K M

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/gt2015109.pdf

Reference23 articles.

1. Pleger SV, Brinks H, Ritterhoff J, Raake P, Koch WJ, Katus HA et al. Heart failure gene therapy: the path to clinical practice. Circ Res 2013; 113: 792–809.

2. Du L, Kido M, Lee DV, Rabinowitz JE, Samulski RJ, Jamieson SW et al. Differential myocardial gene delivery by recombinant serotype-specific adeno-associated viral vectors. Mol Ther 2004; 10: 604–608.

3. Jaski BE, Jessup ML, Mancini DM, Cappola TP, Pauly DF, Greenberg B et al. Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID trial), a first-in-human phase 1/2 clinical trial. J Card Fail 2009; 15: 171–181.

4. Jessup M, Greenberg B, Mancini D, Cappola T, Pauly DF, Jaski B et al. Calcium upregulation by percutaneous administration of gene therapy in cardiac diseases (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum CA2+-ATPase in patients with advanced heart failure. Circulation 2011; 124: 304–313.

5. Zsebo K, Yaroshinsky A, Rudy JJ, Wagner K, Greenberg B, Jessup M et al. Long-term effects of AAV1/SERCA2a gene transfer in patients with severe heart failure. Analysis of recurrent cardiovascular events and mortality. Circ Res 2014; 114: 101–108.

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