Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis-Reference-Cited by-同舟云学术

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Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis

Published:2014-06-15 Issue:7 Volume:20 Page:759-763
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Perry Rachel J,Zhang Xian-Man,Zhang Dongyan,Kumashiro Naoki,Camporez Joao-Paulo G,Cline Gary W,Rothman Douglas L,Shulman Gerald I

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.3579.pdf

Reference37 articles.

1. Fujikawa, T. et al. Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin. Cell Metab. 18, 431–444 (2013).

2. Meek, T.H. et al. Leptin action in the ventromedial hypothalamic nucleus is sufficient, but not necessary, to normalize diabetic hyperglycemia. Endocrinology 154, 3067–3076 (2013).

3. Fujikawa, T., Chuang, J.C., Sakata, I., Ramadori, G. & Coppari, R. Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice. Proc. Natl. Acad. Sci. USA 107, 17391–17396 (2010).

4. Wang, M.Y. et al. Leptin therapy in insulin-deficient type I diabetes. Proc. Natl. Acad. Sci. USA 107, 4813–4819 (2010).

5. Chinookoswong, N., Wang, J.L. & Shi, Z.Q. Leptin restores euglycemia and normalizes glucose turnover in insulin-deficient diabetes in the rat. Diabetes 48, 1487–1492 (1999).

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