Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome
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Published:2016-06-13
Issue:1
Volume:7
Page:
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ISSN:2041-1723
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Container-title:Nature Communications
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language:en
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Short-container-title:Nat Commun
Author:
Machiela Mitchell J.ORCID, Zhou Weiyin, Karlins Eric, Sampson Joshua N., Freedman Neal D., Yang Qi, Hicks BelyndaORCID, Dagnall CaseyORCID, Hautman Christopher, Jacobs Kevin B., Abnet Christian C., Aldrich Melinda C., Amos Christopher, Amundadottir Laufey T., Arslan Alan A., Beane-Freeman Laura E., Berndt Sonja I., Black Amanda, Blot William J., Bock Cathryn H., Bracci Paige M., Brinton Louise A., Bueno-de-Mesquita H Bas, Burdett Laurie, Buring Julie E., Butler Mary A., Canzian FedericoORCID, Carreón Tania, Chaffee Kari G.ORCID, Chang I-Shou, Chatterjee Nilanjan, Chen Chu, Chen Constance, Chen Kexin, Chung Charles C., Cook Linda S., Crous Bou Marta, Cullen Michael, Davis Faith G., De Vivo Immaculata, Ding Ti, Doherty Jennifer, Duell Eric J., Epstein Caroline G., Fan Jin-Hu, Figueroa Jonine D., Fraumeni Joseph F., Friedenreich Christine M., Fuchs Charles S., Gallinger Steven, Gao Yu-Tang, Gapstur Susan M., Garcia-Closas Montserrat, Gaudet Mia M., Gaziano J. Michael, Giles Graham G., Gillanders Elizabeth M., Giovannucci Edward L., Goldin Lynn, Goldstein Alisa M., Haiman Christopher A., Hallmans Goran, Hankinson Susan E., Harris Curtis C., Henriksson Roger, Holly Elizabeth A., Hong Yun-Chul, Hoover Robert N., Hsiung Chao A., Hu Nan, Hu Wei, Hunter David J., Hutchinson Amy, Jenab Mazda, Johansen Christoffer, Khaw Kay-Tee, Kim Hee Nam, Kim Yeul Hong, Kim Young Tae, Klein Alison P., Klein Robert, Koh Woon-Puay, Kolonel Laurence N., Kooperberg Charles, Kraft Peter, Krogh Vittorio, Kurtz Robert C., LaCroix Andrea, Lan Qing, Landi Maria Teresa, Marchand Loic Le, Li Donghui, Liang Xiaolin, Liao Linda M., Lin Dongxin, Liu Jianjun, Lissowska Jolanta, Lu Lingeng, Magliocco Anthony M., Malats Nuria, Matsuo KeitaroORCID, McNeill Lorna H., McWilliams Robert R., Melin Beatrice S., Mirabello Lisa, Moore Lee, Olson Sara H., Orlow Irene, Park Jae Yong, Patiño-Garcia Ana, Peplonska Beata, Peters Ulrike, Petersen Gloria M., Pooler Loreall, Prescott Jennifer, Prokunina-Olsson Ludmila, Purdue Mark P., Qiao You-Lin, Rajaraman Preetha, Real Francisco X., Riboli Elio, Risch Harvey A., Rodriguez-Santiago Benjamin, Ruder Avima M., Savage Sharon A.ORCID, Schumacher Fredrick, Schwartz Ann G., Schwartz Kendra L., Seow Adeline, Wendy Setiawan Veronica, Severi Gianluca, Shen Hongbing, Sheng Xin, Shin Min-Ho, Shu Xiao-Ou, Silverman Debra T., Spitz Margaret R., Stevens Victoria L., Stolzenberg-Solomon Rachael, Stram DanielORCID, Tang Ze-Zhong, Taylor Philip R., Teras Lauren R., Tobias Geoffrey S., Van Den Berg David, Visvanathan Kala, Wacholder Sholom, Wang Jiu-Cun, Wang Zhaoming, Wentzensen Nicolas, Wheeler William, White Emily, Wiencke John K., Wolpin Brian M., Wong Maria Pik, Wu Chen, Wu Tangchun, Wu Xifeng, Wu Yi-Long, Wunder Jay S., Xia Lucy, Yang Hannah P., Yang Pan-Chyr, Yu Kai, Zanetti Krista A., Zeleniuch-Jacquotte Anne, Zheng Wei, Zhou Baosen, Ziegler Regina G., Perez-Jurado Luis A.ORCID, Caporaso Neil E., Rothman Nathaniel, Tucker Margaret, Dean Michael C., Yeager Meredith, Chanock Stephen J.
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Reference40 articles.
1. Strachan, T., Read, A. P. & Strachan, T. Human Molecular Genetics xxv 781Garland Science (2011). 2. Genovese, G. et al. Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence. N. Engl. J. Med. 371, 2477–2487 (2014). 3. Jacobs, K. B. et al. Detectable clonal mosaicism and its relationship to aging and cancer. Nat. Genet. 44, 651–658 (2012). 4. Jaiswal, S. et al. Age-related clonal hematopoiesis associated with adverse outcomes. N. Engl. J. Med. 371, 2488–2498 (2014). 5. Laurie, C. C. et al. Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nat. Genet. 44, 642–650 (2012).
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