Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway-Reference-Cited by-同舟云学术

Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway

Published:2009-01 Issue:1 Volume:5 Page:315
ISSN:1744-4292
Container-title:Molecular Systems Biology
language:en
Short-container-title:Mol Syst Biol

Author:

Miller Bryan W¹²,Lau Garnet¹²,Grouios Chris³,Mollica Emanuela¹,Barrios‐Rodiles Miriam⁴⁵,Liu Yongmei⁴,Datti Alessandro⁵,Morris Quaid²³⁶⁷,Wrana Jeffrey L⁴⁵⁷,Attisano Liliana¹²

Affiliation:

1. Department of Biochemistry, University of Toronto Toronto Ontario Canada

2. Donnelly Centre for Cellular and Biomolecular Research, University of Toronto Toronto Ontario Canada

3. Banting and Best Department of Medical Research, University of Toronto Toronto Ontario Canada

4. Centre for Systems Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital Toronto Ontario Canada

5. Samuel Lunenfeld Research Institute, Mount Sinai Hospital Toronto Ontario Canada

6. Department of Computer Science, University of Toronto Toronto Ontario Canada

7. Department of Molecular Genetics, University of Toronto Toronto Ontario Canada

Publisher

EMBO

Subject

Applied Mathematics,Computational Theory and Mathematics,General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Information Systems

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1038/msb.2009.72

Reference48 articles.

1. The KLHL12–Cullin-3 ubiquitin ligase negatively regulates the Wnt–β-catenin pathway by targeting Dishevelled for degradation

2. High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells

3. Secretion of Wnt Ligands Requires Evi, a Conserved Transmembrane Protein

4. Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate

5. An experimentally derived confidence score for binary protein-protein interactions

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