Design and characterization of bivalent BET inhibitors-Reference-Cited by-同舟云学术

Design and characterization of bivalent BET inhibitors

Published:2016-10-24 Issue:12 Volume:12 Page:1089-1096
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Tanaka Minoru,Roberts Justin M,Seo Hyuk-Soo,Souza Amanda,Paulk Joshiawa,Scott Thomas G,DeAngelo Stephen L,Dhe-Paganon Sirano,Bradner James E

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.2209.pdf

Reference46 articles.

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2. Monsigny, M., Mayer, R. & Roche, A.C. Sugar-lectin interactions: sugar clusters, lectin multivalency and avidity. Carbohydr. Lett. 4, 35–52 (2000).

3. Kiessling, L.L., Gestwicki, J.E. & Strong, L.E. Synthetic multivalent ligands in the exploration of cell-surface interactions. Curr. Opin. Chem. Biol. 4, 696–703 (2000).

4. Bach, A. et al. Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction. Angew. Chem. Int. Ed. Engl. 48, 9685–9689 (2009).

5. Illendula, A. et al. Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice. Science 347, 779–784 (2015).

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