Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43-Reference-Cited by-同舟云学术

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43

Published:2011-02-27 Issue:4 Volume:14 Page:459-468
ISSN:1097-6256
Container-title:Nature Neuroscience
language:en
Short-container-title:Nat Neurosci

Author:

Polymenidou Magdalini,Lagier-Tourenne Clotilde,Hutt Kasey R,Huelga Stephanie C,Moran Jacqueline,Liang Tiffany Y,Ling Shuo-Chien,Sun Eveline,Wancewicz Edward,Mazur Curt,Kordasiewicz Holly,Sedaghat Yalda,Donohue John Paul,Shiue Lily,Bennett C Frank,Yeo Gene W,Cleveland Don W

Publisher

Springer Science and Business Media LLC

Subject

General Neuroscience

Link

http://www.nature.com/articles/nn.2779.pdf

Reference50 articles.

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2. Arai, T. et al. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem. Biophys. Res. Commun. 351, 602–611 (2006).

3. Lagier-Tourenne, C., Polymenidou, M. & Cleveland, D.W. TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration. Hum. Mol. Genet. 19, R46–R64 (2010).

4. Gitcho, M.A. et al. TDP-43 A315T mutation in familial motor neuron disease. Ann. Neurol. 63, 535–538 (2008).

5. Kabashi, E. et al. TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. Nat. Genet. 40, 572–574 (2008).

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