Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans-Reference-Cited by-同舟云学术

Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans

Published:2008-06 Issue:6 Volume:14 Page:617-621
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Watkins David I,Burton Dennis R,Kallas Esper G,Moore John P,Koff Wayne C

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.f.1759.pdf

Reference76 articles.

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2. Mascola, J.R. et al. Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies. Nat. Med. 6, 207–210 (2000).

3. Parren, P.W. et al. Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro. J. Virol. 75, 8340–8347 (2001).

4. Deeks, S.G. & Walker, B.D. Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity 27, 406–416 (2007).

5. VaxGen. VaxGen announces results of its phase 3 HIV vaccine trial in Thailand: vaccine fails to meet endpoints. < http://investor.vaxgen.com/profiles/investor/ResLibraryView.asp?ResLibraryID=5836&GoTopage=16&BzID=923&Category=214 > (2003).

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