PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression-Reference-Cited by-同舟云学术

PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression

Published:2016-10-24 Issue:11 Volume:22 Page:1321-1329
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Horiuchi Dai,Camarda Roman,Zhou Alicia Y,Yau Christina,Momcilovic Olga,Balakrishnan Sanjeev,Corella Alexandra N,Eyob Henok,Kessenbrock Kai,Lawson Devon A,Marsh Lindsey A,Anderton Brittany N,Rohrberg Julia,Kunder Ratika,Bazarov Alexey V,Yaswen Paul,McManus Michael T,Rugo Hope S,Werb Zena,Goga Andrei

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.4213.pdf

Reference51 articles.

1. Foulkes, W.D., Smith, I.E. & Reis-Filho, J.S. Triple-negative breast cancer. N. Engl. J. Med. 363, 1938–1948 (2010).

2. Horiuchi, D. et al. MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition. J. Exp. Med. 209, 679–696 (2012).

3. Prochownik, E.V. & Vogt, P.K. Therapeutic targeting of Myc. Genes Cancer 1, 650–659 (2010).

4. Kaelin, W.G. Jr . The concept of synthetic lethality in the context of anticancer therapy. Nat. Rev. Cancer 5, 689–698 (2005).

5. Mukhopadhyay, R. et al. Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies. Breast Cancer Res. 12, R11 (2010).

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