Short and dysfunctional telomeres sensitize the kidneys to develop fibrosis
Author:
Funder
European Research Council
Publisher
Springer Science and Business Media LLC
Subject
Pulmonary and Respiratory Medicine,Pediatrics, Perinatology, and Child Health
Link
http://www.nature.com/articles/s43587-021-00040-8.pdf
Reference72 articles.
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2. Humphreys, B. D. Mechanisms of renal fibrosis. Annu. Rev. Physiol. 80, 309–326 (2018).
3. Dongre, A. & Weinberg, R. A. New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer. Nat. Rev. Mol. Cell Biol. 20, 69–84 (2019).
4. Grande, M. T. et al. Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease. Nat. Med. 21, 989–997 (2015).
5. Inoue, T., Okada, H., Takenaka, T., Watanabe, Y. & Suzuki, H. A case report suggesting the occurrence of epithelial–mesenchymal transition in obstructive nephropathy. Clin. Exp. Nephrol. 13, 385–388 (2009).
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