ADAMANT: a placebo-controlled randomized phase 2 study of AADvac1, an active immunotherapy against pathological tau in Alzheimer’s disease-Reference-Cited by-同舟云学术

ADAMANT: a placebo-controlled randomized phase 2 study of AADvac1, an active immunotherapy against pathological tau in Alzheimer’s disease

Published:2021-06 Issue:6 Volume:1 Page:521-534
ISSN:2662-8465
Container-title:Nature Aging
language:en
Short-container-title:Nat Aging

Author:

Novak Petr^ORCID,Kovacech Branislav^ORCID,Katina Stanislav,Schmidt Reinhold,Scheltens Philip^ORCID,Kontsekova Eva,Ropele Stefan^ORCID,Fialova Lubica,Kramberger Milica,Paulenka-Ivanovova Natalia,Smisek Miroslav,Hanes Jozef,Stevens Eva,Kovac Andrej,Sutovsky Stanislav,Parrak Vojtech,Koson Peter,Prcina Michal,Galba Jaroslav,Cente Martin^ORCID,Hromadka Tomas,Filipcik Peter,Piestansky Juraj,Samcova Maria,Prenn-Gologranc Carmen,Sivak Roman,Froelich Lutz,Fresser Michal,Rakusa Martin^ORCID,Harrison John^ORCID,Hort Jakub,Otto Markus^ORCID,Tosun Duygu^ORCID,Ondrus Matej,Winblad Bengt^ORCID,Novak Michal,Zilka Norbert

Publisher

Springer Science and Business Media LLC

Subject

Pulmonary and Respiratory Medicine,Pediatrics, Perinatology, and Child Health

Link

http://www.nature.com/articles/s43587-021-00070-2.pdf

Reference67 articles.

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3. Grundke-Iqbal, I. et al. Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc. Natl Acad. Sci. USA 83, 4913–4917 (1986).

4. Whitwell, J. L. et al. Neuroimaging correlates of pathologically defined subtypes of Alzheimer’s disease: a case-control study. Lancet Neurol. 11, 868–877 (2012).

5. Nelson, P. T. et al. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. J. Neuropathol. Exp. Neurol. 71, 362–381 (2012).

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