Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/416878a.pdf
Reference30 articles.
1. Siderovski, D. P., Diversé-Pierluissi, M. A. & De Vries, L. The GoLoco motif: a Gα-i/o binding motif and potential guanine-nucleotide exchange factor. Trends Biochem. Sci. 24, 340–341 (1999).
2. Takesono, A. et al. Receptor-independent activators of heterotrimeric G-protein signalling pathways. J. Biol. Chem. 274, 33202–33205 (1999).
3. De Vries, L. et al. Activator of G protein signalling 3 is a guanine dissociation inhibitor for Gα i subunits. Proc. Natl Acad. Sci. USA 97, 14364–14369 (2000).
4. Natochin, M. et al. AGS3 inhibits GDP dissociation from Gα subunits of the Gi family and rhodopsin-dependent activation of transducin. J. Biol. Chem. 275, 40981–40985 (2000).
5. Kimple, R. J. et al. RGS12 and RGS14 GoLoco motifs are Gαi interaction sites with guanine nucleotide dissociation inhibitor activity. J. Biol. Chem. 276, 29275–29281 (2001).
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