Precision is essential for efficient catalysis in an evolved Kemp eliminase-Reference-Cited by-同舟云学术

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Precision is essential for efficient catalysis in an evolved Kemp eliminase

Published:2013-10-16 Issue:7476 Volume:503 Page:418-421
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Blomberg Rebecca,Kries Hajo,Pinkas Daniel M.,Mittl Peer R. E.,Grütter Markus G.,Privett Heidi K.,Mayo Stephen L.,Hilvert Donald

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature12623.pdf

Reference47 articles.

1. Pauling, L. Molecular architecture and biological reactions. Chem. Eng. News 24, 1375–1377 (1946)

2. Hilvert, D. Critical analysis of antibody catalysis. Annu. Rev. Biochem. 69, 751–793 (2000)

3. Privett, H. K. et al. Iterative approach to computational enzyme design. Proc. Natl Acad. Sci. USA 109, 3790–3795 (2012)

4. Albery, W. J. & Knowles, J. R. Free-energy profile for the reaction catalyzed by triosephosphate isomerase. Biochemistry 15, 5627–5631 (1976)

5. Blacklow, S. C., Raines, R. T., Lim, W. A., Zamore, P. D. & Knowles, J. R. Triosephosphate isomerase catalysis is diffusion controlled. Biochemistry 27, 1158–1165 (1988)

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