Structure of the human smoothened receptor bound to an antitumour agent-Reference-Cited by-同舟云学术

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Structure of the human smoothened receptor bound to an antitumour agent

Published:2013-05 Issue:7449 Volume:497 Page:338-343
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Wang Chong,Wu Huixian,Katritch Vsevolod,Han Gye Won,Huang Xi-Ping,Liu Wei,Siu Fai Yiu,Roth Bryan L.,Cherezov Vadim,Stevens Raymond C.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature12167.pdf

Reference49 articles.

1. Ingham, P. W. & McMahon, A. P. Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 15, 3059–3087 (2001)

2. Robbins, D. J., Fei, D. L. & Riobo, N. A. The Hedgehog signal transduction network. Sci. Signal. 5, re6 (2012)

3. Marigo, V., Davey, R. A., Zuo, Y., Cunningham, J. M. & Tabin, C. J. Biochemical evidence that patched is the Hedgehog receptor. Nature 384, 176–179 (1996)

4. Stone, D. M. et al. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature 384, 129–134 (1996)

5. Taipale, J., Cooper, M. K., Maiti, T. & Beachy, P. A. Patched acts catalytically to suppress the activity of Smoothened. Nature 418, 892–896 (2002)

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