Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling-Reference-Cited by-同舟云学术

Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling

Published:2013-05 Issue:7451 Volume:497 Page:638-642
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Zimmermann Gunther,Papke Björn,Ismail Shehab,Vartak Nachiket,Chandra Anchal,Hoffmann Maike,Hahn Stephan A.,Triola Gemma,Wittinghofer Alfred,Bastiaens Philippe I. H.,Waldmann Herbert

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature12205.pdf

Reference26 articles.

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3. Downward, J. Targeting RAS signalling pathways in cancer therapy. Nature Rev. Cancer 3, 11–22 (2003)

4. Berndt, N., Hamilton, A. D. & Sebti, S. M. Targeting protein prenylation for cancer therapy. Nature Rev. Cancer 11, 775–791 (2011)

5. Roberts, P. J. & Der, C. J. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 26, 3291–3310 (2007)

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