Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response-Reference-Cited by-同舟云学术

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Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response

Published:2014-08-03 Issue:9 Volume:20 Page:1001-1008
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Yan Jingqi,Zhang Hai,Yin Ye,Li Juxue,Tang Yizhe,Purkayastha Sudarshana,Li Lianxi,Cai Dongsheng

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.3616.pdf

Reference66 articles.

1. Samuel, V.T. & Shulman, G.I. Mechanisms for insulin resistance: common threads and missing links. Cell 148, 852–871 (2012).

2. Gregor, M.F. & Hotamisligil, G.S. Inflammatory mechanisms in obesity. Annu. Rev. Immunol. 29, 415–445 (2011).

3. Muoio, D.M. & Newgard, C.B. Obesity-related derangements in metabolic regulation. Annu. Rev. Biochem. 75, 367–401 (2006).

4. Glass, C.K. & Olefsky, J.M. Inflammation and lipid signaling in the etiology of insulin resistance. Cell Metab. 15, 635–645 (2012).

5. Mighiu, P.I. et al. Hypothalamic glucagon signaling inhibits hepatic glucose production. Nat. Med. 19, 766–772 (2013).

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