Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition-Reference-Cited by-同舟云学术

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Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition

Published:2017-02-16 Issue:1 Volume:7 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Hardeman Keisha N.,Peng Chengwei,Paudel Bishal B.,Meyer Christian T.,Luong Thong,Tyson Darren R.,Young Jamey D.,Quaranta Vito,Fessel Joshua P.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep42604.pdf

Reference56 articles.

1. Davies, H. et al. Mutations of the BRAF gene in human cancer. Nature 417, 949–954 (2002).

2. Ribas, A. & Flaherty, K. T. BRAF targeted therapy changes the treatment paradigm in melanoma. Nat. Rev. Clin. Oncol. 8, 426–433 (2011).

3. Ascierto, P. A. et al. The role of BRAF V600 mutation in melanoma. J. Transl. Med. 10, 85 (2012).

4. Chapman, P. B. et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N. Engl. J. Med. 364, 2507–2516 (2011).

5. Chan, M. M. K. et al. The nature and management of metastatic melanoma after progression on braf inhibitors: Effects of extended BRAF inhibition. Cancer 120, 3142–3153 (2014).

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