Effects of FVIII immunity on hepatocyte and hematopoietic stem cell–directed gene therapy of murine hemophilia A-Reference-Cited by-同舟云学术

Effects of FVIII immunity on hepatocyte and hematopoietic stem cell–directed gene therapy of murine hemophilia A

Published:2016 Issue: Volume:3 Page:15056
ISSN:2329-0501
Container-title:Molecular Therapy - Methods & Clinical Development
language:en
Short-container-title:Molecular Therapy - Methods & Clinical Development

Author:

Lytle Allison M,Brown Harrison C,Paik Na Yoon,Knight Kristopher A,Wright J Fraser,Spencer H Trent,Doering Christopher B

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference61 articles.

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1. Ultrasound-mediated gene delivery specifically targets liver sinusoidal endothelial cells for sustained FVIII expression in hemophilia A mice;Molecular Therapy;2024-04

2. Transplanting FVIII/ET3-secreting cells in fetal sheep increases FVIII levels long-term without inducing immunity or toxicity;Nature Communications;2023-07-14

3. Autologous bone marrow-derived MSCs engineered to express oFVIII-FLAG engraft in adult sheep and produce an effective increase in plasma FVIII levels;Frontiers in Immunology;2022-12-02

4. Hemophilia A/B;Hematology/Oncology Clinics of North America;2022-08

5. Pharmacokinetic analysis identifies a factor VIII immunogenicity threshold after AAV gene therapy in hemophilia A mice;Blood Advances;2022-04-22