Tightening of the ATP-binding sites induces the opening of P2X receptor channels
Author:
Affiliation:
1. Faculté de Pharmacie, Laboratoire de Biophysicochimie des Récepteurs Canaux, UMR 7199 CNRS, Conception et Application de Molécules Bioactives, Université de Strasbourg; Illkirch France
Publisher
Wiley
Subject
General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience
Reference55 articles.
1. ADP-ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site;Adriouch;FASEB J,2008
2. Analysis of zinc binding sites in protein crystal structures;Alberts;Protein Sci,1998
3. The alpha7 nicotinic acetylcholine receptor: molecular modelling, electrostatics, and energetics;Amiri;Mol Membr Biol,2005
4. Dynamics of proteins and biomolecular complexes: inferring functional motions from structure;Bahar;Rev Chem Eng,1999
5. Coarse-grained normal mode analysis in structural biology;Bahar;Curr Opin Struct Biol,2005
Cited by 73 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A shared mechanism for TNP-ATP recognition by members of the P2X receptor family;Computational and Structural Biotechnology Journal;2024-12
2. High-affinity agonism at the P2X7 receptor is mediated by three residues outside the orthosteric pocket;Nature Communications;2024-08-06
3. Exploring P2x Receptor Activity: A Journey from Cellular Impact to Electrophysiological Profiling;2024
4. Structure–function and pharmacologic aspects of ion channels relevant to neurologic channelopathies;Handbook of Clinical Neurology;2024
5. Druggable site near the upper vestibule determines the high affinity and P2X3 homotrimer selectivity of sivopixant/S‐600918 and its analogue DDTPA;British Journal of Pharmacology;2023-12-07
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3