The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

Author:

Zhang Kezhong123,Wang Shiyu1,Malhotra Jyoti1,Hassler Justin R1,Back Sung Hoon4,Wang Guohui2,Chang Lin5,Xu Wenbo2,Miao Hongzhi6,Leonardi Roberta7,Chen Y Eugene5,Jackowski Suzanne7,Kaufman Randal J18

Affiliation:

1. Department of Biological Chemistry, University of Michigan Medical Center; Ann Arbor MI USA

2. Center for Molecular Medicine and Genetics, Wayne State University School of Medicine; Detroit MI USA

3. Department of Immunology and Microbiology, Wayne State University School of Medicine; Detroit MI USA

4. Howard Hughes Medical Institute, University of Michigan Medical Center; Ann Arbor MI USA

5. Cardiovascular Medicine, University of Michigan Medical Center; Ann Arbor MI USA

6. Department of Pediatrics, University of Michigan Medical Center; Ann Arbor MI USA

7. Department of infectious Diseases, St Jude Children's Research Hospital; Memphis TN USA

8. Department of Internal Medicine, University of Michigan Medical Center; Ann Arbor MI USA

Publisher

Wiley

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Reference93 articles.

1. Enzymatic determination of total serum cholesterol;Allain;Clin Chem,1974

2. Isolated hepatocytes preparation, properties and applications;Berry;Laboratory Techniques in Biochemistry and Molecular Biology,1991

3. Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein;Brasaemle;J Lipid Res,1997

4. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA;Calfon;Nature,2002

5. Translational control of C/EBPalpha and C/EBPbeta isoform expression;Calkhoven;Genes Dev,2000

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