NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression

Author:

Reynolds Nicola1,Salmon-Divon Mali23,Dvinge Heidi24,Hynes-Allen Antony1,Balasooriya Gayan1,Leaford Donna1,Behrens Axel5,Bertone Paul26,Hendrich Brian17

Affiliation:

1. Wellcome Trust Centre for Stem Cell Research and MRC Centre for Stem Cell Biology and Regenerative Medicine, University of Cambridge; Cambridge UK

2. EMBL European Bioinformatics Institute; Cambridge UK

3. Cancer Research Center, Chaim Sheba Medical Center; Tel Hashomer Israel

4. Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre; Cambridge UK

5. London Research Institute, Lincoln's Inn Fields Laboratories; London UK

6. Genome Biology and Developmental Biology Units, EMBL; Heidelberg Germany

7. Department of Biochemistry, University of Cambridge; Cambridge UK

Publisher

Wiley

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Reference71 articles.

1. CHD3 proteins and polycomb group proteins antagonistically determine cell identity in Arabidopsis;Aichinger;PLoS Genet,2009

2. Chromatin signatures of pluripotent cell lines;Azuara;Nat Cell Biol,2006

3. A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data;Barbosa-Morais;Nucleic Acids Res,2010

4. Controlling the false discovery rate: a practical and powerful approach to multiple testing;Benjamini;J R Stat Soc Ser B Stat Methodol,1995

5. The complex language of chromatin regulation during transcription;Berger;Nature,2007

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