Generation of reduced macrolide analogs by regio-specific biotransformation-Reference-Cited by-同舟云学术

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Generation of reduced macrolide analogs by regio-specific biotransformation

Published:2010-11-24 Issue:1 Volume:64 Page:155-157
ISSN:0021-8820
Container-title:The Journal of Antibiotics
language:en
Short-container-title:J Antibiot

Author:

Park Je Won,Park Sung Ryeol,Han Ah Reum,Ban Yeon-Hee,Yoo Young Ji,Kim Eun Ji,Kim Eunji,Yoon Yeo Joon

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

http://www.nature.com/articles/ja2010143.pdf

Reference13 articles.

1. Fischbach, M. A. & Walsh, C. T. Antibiotics for emerging pathogens. Science 325, 1089–1093 (2009).

2. Saleem, M. et al. Antimicrobial natural products: an update on future antibiotic drug candidates. Nat. Prod. Rep. 27, 238–254 (2010).

3. Smith, R. A., Peterson, W. H. & McCoy, E. Oligomycin, a new antifungal antibiotic. Antibiot. Chemother. 4, 962–970 (1954).

4. Li, Y. C. et al. Mitochondria-targeting drug oligomycin blocked P-glycoprotein activity and triggered apoptosis in doxorubicin-resistant HepG2 cells. Chemotherapy 50, 55–62 (2004).

5. Debono, M. et al. Synthesis and antimicrobial evaluation of 20-deoxo-20-(3,5-dimethylpiperidin-1-yl)desmycosin (tilmicosin, EL-870) and related cyclic amino derivatives. J. Antibiot. 42, 1253–1267 (1989).

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