Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase-Reference-Cited by-同舟云学术

Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

Published:2011-08-17 Issue:7363 Volume:477 Page:225-228
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Frezza Christian,Zheng Liang,Folger Ori,Rajagopalan Kartik N.,MacKenzie Elaine D.,Jerby Livnat,Micaroni Massimo,Chaneton Barbara,Adam Julie,Hedley Ann,Kalna Gabriela,Tomlinson Ian P. M.,Pollard Patrick J.,Watson Dave G.,Deberardinis Ralph J.,Shlomi Tomer,Ruppin Eytan,Gottlieb Eyal

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature10363.pdf

Reference24 articles.

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3. Pollard, P. J. et al. Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway. Cancer Cell 11, 311–319 (2007)

4. Frezza, C., Pollard, P. J. & Gottlieb, E. Inborn and acquired metabolic defects in cancer. J. Mol. Med. 89, 213–220 (2011)

5. DeBerardinis, R. J. et al. Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc. Natl Acad. Sci. USA 104, 19345–19350 (2007)

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