Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF-Reference-Cited by-同舟云学术

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Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF

Published:2011-07 Issue:7356 Volume:475 Page:408-411
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Mackereth Cameron D.,Madl Tobias,Bonnal Sophie,Simon Bernd,Zanier Katia,Gasch Alexander,Rybin Vladimir,Valcárcel Juan,Sattler Michael

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature10171.pdf

Reference36 articles.

1. Zamore, P. D., Patton, J. G. & Green, M. R. Cloning and domain structure of the mammalian splicing factor U2AF. Nature 355, 609–614 (1992)

2. Banerjee, H., Rahn, A., Davis, W. & Singh, R. Sex lethal and U2 small nuclear ribonucleoprotein auxiliary factor (U2AF65) recognize polypyrimidine tracts using multiple modes of binding. RNA 9, 88–99 (2003)

3. Banerjee, H. et al. The conserved RNA recognition motif 3 of U2 snRNA auxiliary factor (U2AF65) is essential in vivo but dispensible for activity in vitro . RNA 10, 240–253 (2004)

4. Wahl, M. C., Will, C. L. & Lührmann, R. The spliceosome: design principles of a dynamic RNP machine. Cell 136, 701–718 (2009)

5. Reed, R. The organization of 3′ splice-site sequences in mammalian introns. Genes Dev. 3, 2113–2123 (1989)

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