Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection-Reference-Cited by-同舟云学术

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Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection

Published:2011-08-24 Issue:7364 Volume:477 Page:344-348
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Côté Marceline,Misasi John,Ren Tao,Bruchez Anna,Lee Kyungae,Filone Claire Marie,Hensley Lisa,Li Qi,Ory Daniel,Chandran Kartik,Cunningham James

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature10380.pdf

Reference30 articles.

1. Zampieri, C. A., Sullivan, N. J. & Nabel, G. J. Immunopathology of highly virulent pathogens: insights from Ebola virus. Nature Immunol. 8, 1159–1164 (2007)

2. Geisbert, T. W. & Jahrling, P. B. Exotic emerging viral diseases: progress and challenges. Nature Med. 10, S110–S121 (2004)

3. Chandran, K., Sullivan, N. J., Felbor, U., Whelan, S. P. & Cunningham, J. M. Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. Science 308, 1643–1645 (2005)

4. Schornberg, K. et al. Role of endosomal cathepsins in entry mediated by the Ebola virus glycoprotein. J. Virol. 80, 4174–4178 (2006)

5. Lee, J. E. et al. Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor. Nature 454, 177–182 (2008)

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