Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine-Reference-Cited by-同舟云学术

Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

Published:2012-12-02 Issue:1 Volume:19 Page:83-92
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Kim Kook Hwan,Jeong Yeon Taek,Oh Hyunhee,Kim Seong Hun,Cho Jae Min,Kim Yo-Na,Kim Su Sung,Kim Do Hoon,Hur Kyu Yeon,Kim Hyoung Kyu,Ko TaeHee,Han Jin,Kim Hong Lim,Kim Jin,Back Sung Hoon,Komatsu Masaaki,Chen Hsiuchen,Chan David C,Konishi Morichika,Itoh Nobuyuki,Choi Cheol Soo,Lee Myung-Shik

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.3014.pdf

Reference60 articles.

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2. Ebato, C. et al. Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet. Cell Metab. 8, 325–332 (2008).

3. Jung, H.S. et al. Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia. Cell Metab. 8, 318–324 (2008).

4. Singh, R. et al. Autophagy regulates lipid metabolism. Nature 458, 1131–1135 (2009).

5. Singh, R. et al. Autophagy regulates adipose mass and differentiation in mice. J. Clin. Invest. 119, 3329–3339 (2009).

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