Initial sites of hepadnavirus integration into host genome in human hepatocytes and in the woodchuck model of hepatitis B-associated hepatocellular carcinoma

Author:

Chauhan R,Churchill N D,Mulrooney-Cousins P M,Michalak T I

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology

Reference64 articles.

1. World Health Organization. Hepatitis B fact sheet. Revised July. World Health Organization: Geneva, Switzerland, 2015, Available http://www.who.int/mediacentre/factsheets/fs204/en/ . Accessed: 10 April 2016.

2. Yang JD, Roberts LR . Hepatocellular carcinoma: a global view. Nat Rev Gastroenterol Hepatol 2010; 7: 448–458.

3. Ranjit C, Lahiri N . Tissue and serum-associated biomarkers of hepatocellular carcinoma. Biomark Cancer 2016; 8: 37–55.

4. Wollersheim M, Debelka U, Hofschneider PH . A transactivating function encoded in the hepatitis B virus X gene is conserved in the integrated state. Oncogene 1988; 3: 545–552.

5. Levrero M, Zucman-Rossi J . Mechanisms of HBV-induced hepatocellular carcinoma. J Hepatol 2016; 64: S84–S101.

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