Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy-Reference-Cited by-同舟云学术

Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy

Published:2018-03-05 Issue:4 Volume:24 Page:427-437
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Badders Nisha M,Korff Ane,Miranda Helen C,Vuppala Pradeep K,Smith Rebecca B,Winborn Brett J,Quemin Emmanuelle R,Sopher Bryce L,Dearman Jennifer,Messing James,Kim Nam Chul,Moore Jennifer,Freibaum Brian D,Kanagaraj Anderson P,Fan Baochang,Tillman Heather^ORCID,Chen Ping-Chung,Wang Yingzhe,III Burgess B Freeman,Li Yimei,Kim Hong Joo,La Spada Albert R,Taylor J Paul

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.4500.pdf

Reference53 articles.

1. Kennedy, W.R., Alter, M. & Sung, J.H. Progressive proximal spinal and bulbar muscular atrophy of late onset. A sex-linked recessive trait. Neurology 18, 671–680 (1968).

2. Chahin, N., Klein, C., Mandrekar, J. & Sorenson, E. Natural history of spinal-bulbar muscular atrophy. Neurology 70, 1967–1971 (2008).

3. Poletti, A., Negri-Cesi, P. & Martini, L. Reflections on the diseases linked to mutations of the androgen receptor. Endocrine 28, 243–262 (2005).

4. Fratta, P. et al. Correlation of clinical and molecular features in spinal bulbar muscular atrophy. Neurology 82, 2077–2084 (2014).

5. La Spada, A.R., Wilson, E.M., Lubahn, D.B., Harding, A.E. & Fischbeck, K.H. Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature 352, 77–79 (1991).

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