The epigenetic regulator UHRF1 promotes ubiquitination-mediated degradation of the tumor-suppressor protein promyelocytic leukemia protein
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2012406.pdf
Reference53 articles.
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2. Avvakumov GV, Walker JR, Xue S, Li Y, Duan S, Bronner C et al. Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1. Nature 2008; 455: 822–825.
3. Hashimoto H, Horton JR, Zhang X, Bostick M, Jacobsen SE, Cheng X . The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix. Nature 2008; 455: 826–829.
4. Bostick M, Kim JK, Esteve PO, Clark A, Pradhan S, Jacobsen SE . UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science 2007; 317: 1760–1764.
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