Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer-Reference-Cited by-同舟云学术

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Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer

Published:2012-05-21 Issue:13 Volume:32 Page:1638-1650
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Sutendra G,Dromparis P,Kinnaird A,Stenson T H,Haromy A,Parker J M R,McMurtry M S,Michelakis E D

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc2012198.pdf

Reference75 articles.

1. Gatenby RA, Gillies RJ . Why do cancers have high aerobic glycolysis? Nat Rev Cancer 2004; 4: 891–899.

2. Michelakis ED, Webster L, Mackey JR . Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer. Br J Cancer 2008; 99: 989–994.

3. Pan JG, Mak TW . Metabolic targeting as an anticancer strategy: dawn of a new era? Sci STKE 2007; 2007: pe14.

4. Vander Heiden MG, Cantley LC, Thompson CB . Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009; 324: 1029–1033.

5. Dromparis P, Sutendra G, Michelakis ED . The role of mitochondria in pulmonary vascular remodeling. J Mol Med 2010; 88: 1003–1010.

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