The chemotherapeutic agent paclitaxel inhibits autophagy through two distinct mechanisms that regulate apoptosis-Reference-Cited by-同舟云学术

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The chemotherapeutic agent paclitaxel inhibits autophagy through two distinct mechanisms that regulate apoptosis

Published:2012-03-19 Issue:6 Volume:32 Page:736-746
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Veldhoen R A,Banman S L,Hemmerling D R,Odsen R,Simmen T,Simmonds A J,Underhill D A,Goping I S

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc201292.pdf

Reference40 articles.

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2. Jordan MA, Toso RJ, Thrower D, Wilson L . Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Proc Natl Acad Sci USA 1993; 90: 9552–9556.

3. Craik AC, Veldhoen RA, Czernick M, Buckland TW, Kyselytzia K, Ghosh S et al. The BH3-only protein Bad confers breast cancer taxane sensitivity through a nonapoptotic mechanism. Oncogene 2010; 29: 5381–5391.

4. Shi J, Orth JD, Mitchison T . Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5. Cancer Res 2008; 68: 3269–3276.

5. Gorka M, Daniewski WM, Gajkowska B, Lusakowska E, Godlewski MM, Motyl T . Autophagy is the dominant type of programmed cell death in breast cancer MCF-7 cells exposed to AGS 115 and EFDAC, new sesquiterpene analogs of paclitaxel. Anticancer Drugs 2005; 16: 777–788.

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