Combination of MEK and SRC inhibition suppresses melanoma cell growth and invasion
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc201225.pdf
Reference52 articles.
1. Wellbrock C, Hurlstone A . BRAF as therapeutic target in melanoma. Biochem Pharmacol 2010; 80: 561–567.
2. Bollag G, Hirth P, Tsai J, Zhang J, Ibrahim PN, Cho H et al. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature 2010; 467: 596–599.
3. Heidorn SJ, Milagre C, Whittaker S, Nourry A, Niculescu-Duvas I, Dhomen N et al. Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF. Cell 2010; 140: 209–221.
4. Puzanov I, Burnett P, Flaherty KT . Biological challenges of BRAF inhibitor therapy. Mol Oncol 2011; 5: 116–123.
5. Yeh TC, Marsh V, Bernat BA, Ballard J, Colwell H, Evans RJ et al. Biological characterization of ARRY-142886 (AZD6244), a potent, highly selective mitogen-activated protein kinase kinase 1/2 inhibitor. Clin Cancer Res 2007; 13: 1576–1583.
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