Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2012210.pdf
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3. Hruban RH, Adsay NV, Albores-Saavedra J, Compton C, Garrett ES, Goodman SN et al. Pancreatic intraepithelial neoplasia—a new nomenclature and classification system for pancreatic duct lesions. Am J Surg Pathol 2001; 25: 579–586.
4. Shi G, Zhu L, Sun Y, Bettencourt R, Damsz B, Hruban RH et al. Loss of the acinar-restricted transcription factor Mist1 accelerates Kras-induced pancreatic intraepithelial neoplasia. Gastroenterology 2009; 136: 1368–1378.
5. Guerra C, Mijimolle N, Dhawahir A, Dubus P, Barradas M, Serrano M et al. Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context. Cancer Cell 2003; 4: 111–120.
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