The tumour suppressor HACE1 controls cell migration by regulating Rac1 degradation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2012189.pdf
Reference19 articles.
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3. Visvikis O, Lores P, Boyer L, Chardin P, Lemichez E, Gacon G . Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process. Febs J 2008; 275: 386–396.
4. Lynch EA, Stall J, Schmidt G, Chavrier P, D'Souza-Schorey C . Proteasome-mediated degradation of Rac1-GTP during epithelial cell scattering. Mol Biol Cell 2006; 17: 2236–2242.
5. Nethe M, Anthony EC, Fernandez-Borja M, Dee R, Geerts D, Hensbergen PJ et al. Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathway. J Cell Sci 2010; 123: 1948–1958.
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