Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis-Reference-Cited by-同舟云学术

Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis

Published:2012-10-22 Issue:39 Volume:32 Page:4675-4682
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Christie M,Jorissen R N,Mouradov D,Sakthianandeswaren A,Li S,Day F,Tsui C,Lipton L,Desai J,Jones I T,McLaughlin S,Ward R L,Hawkins N J,Ruszkiewicz A R,Moore J,Burgess A W,Busam D,Zhao Q,Strausberg R L,Simpson A J,Tomlinson I P M,Gibbs P,Sieber O M

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc2012486.pdf

Reference33 articles.

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2. Powell SM, Zilz N, Beazer-Barclay Y, Bryan TM, Hamilton SR, Thibodeau SN et al. APC mutations occur early during colorectal tumorigenesis. Nature 1992; 359: 235–237.

3. Groden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, Albertsen H et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell 1991; 66: 589–600.

4. Nathke IS . The adenomatous polyposis coli protein: the achilles heel of the gut epithelium. Annu Rev Cell Dev Biol 2004; 20: 337–366.

5. Klaus A, Birchmeier W . Wnt signalling and its impact on development and cancer. Nat Rev Cancer 2008; 8: 387–398.

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