A potent Chk1 inhibitor is selectively cytotoxic in melanomas with high levels of replicative stress-Reference-Cited by-同舟云学术

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A potent Chk1 inhibitor is selectively cytotoxic in melanomas with high levels of replicative stress

Published:2012-03-05 Issue:6 Volume:32 Page:788-796
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Brooks K,Oakes V,Edwards B,Ranall M,Leo P,Pavey S,Pinder A,Beamish H,Mukhopadhyay P,Lambie D,Gabrielli B

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc201272.pdf

Reference41 articles.

1. McDonald 3rd ER, El-Deiry WS . Checkpoint genes in cancer. Ann Med 2001; 33: 113–122.

2. Stewart ZA, Westfall MD, Pietenpol JA . Cell-cycle dysregulation and anticancer therapy. Trends Pharmacol Sci 2003; 24: 139–145.

3. Lazzaro F, Giannattasio M, Puddu F, Granata M, Pellicioli A, Plevani P et al. Checkpoint mechanisms at the intersection between DNA damage and repair. DNA Repair (Amst) 2009; 8: 1055–1067.

4. Kaelin WG Jr . The concept of synthetic lethality in the context of anticancer therapy. Nat Rev Cancer 2005; 5: 689–698.

5. Dai Y, Grant S . New insights into checkpoint kinase 1 in the DNA damage response signaling network. Clin Cancer Res 2010; 16: 376–383.

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