Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-to-mesenchymal transition in an orthotopic model
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2012413.pdf
Reference47 articles.
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3. Besmer DM, Curry JM, Roy LD, Tinder TL, Sahraei M, Schettini J et al. Pancreatic ductal adenocarcinoma mice lacking mucin 1 have a profound defect in tumor growth and metastasis. Cancer Res 2011; 71: 4432–4442.
4. Cates JM, Byrd RH, Fohn LE, Tatsas AD, Washington MK, Black CC . Epithelial-mesenchymal transition markers in pancreatic ductal adenocarcinoma. Pancreas 2009; 38: e1–e6.
5. Javle MM, Gibbs JF, Iwata KK, Pak Y, Rutledge P, Yu J et al. Epithelial-mesenchymal transition (EMT) and activated extracellular signal-regulated kinase (p-Erk) in surgically resected pancreatic cancer. Ann Surg Oncol 2007; 14: 3527–3533.
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