Conditional activation of Pik3caH1047R in a knock-in mouse model promotes mammary tumorigenesis and emergence of mutations-Reference-Cited by-同舟云学术

Conditional activation of Pik3caH1047R in a knock-in mouse model promotes mammary tumorigenesis and emergence of mutations

Published:2012-02-27 Issue:3 Volume:32 Page:318-326
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Yuan W,Stawiski E,Janakiraman V,Chan E,Durinck S,Edgar K A,Kljavin N M,Rivers C S,Gnad F,Roose-Girma M,Haverty P M,Fedorowicz G,Heldens S,Soriano R H,Zhang Z,Wallin J J,Johnson L,Merchant M,Modrusan Z,Stern H M,Seshagiri S

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc201253.pdf

Reference53 articles.

1. Cantley LC . The phosphoinositide 3-kinase pathway. Science 2002; 296: 1655–1657.

2. Hawkins PT, Anderson KE, Davidson K, Stephens LR . Signalling through Class I PI3Ks in mammalian cells. Biochem Soc Trans 2006; 34: 647–662.

3. Vanhaesebroeck B, Ali K, Bilancio A, Geering B, Foukas LC . Signalling by PI3K isoforms: insights from gene-targeted mice. Trends Biochem Sci 2005; 30: 194–204.

4. Samuels Y, Wang Z, Bardelli A, Silliman N, Ptak J, Szabo S et al. High frequency of mutations of the PIK3CA gene in human cancers. Science 2004; 304: 554.

5. Bachman KE, Argani P, Samuels Y, Silliman N, Ptak J, Szabo S et al. The PIK3CA gene is mutated with high frequency in human breast cancers. Cancer Biol Ther 2004; 3: 772–775.

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