The growing complexity of HIF-1α’s role in tumorigenesis: DNA repair and beyond
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2012510.pdf
Reference114 articles.
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2. Keith B, Johnson RS, Simon MC . HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression. Nat Rev Cancer 2011; 12: 9–22.
3. Wang GL, Semenza GL . Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 1995; 270: 1230–1237.
4. Wang GL, Jiang BH, Rue EA, Semenza GL . Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 1995; 92: 5510–5514.
5. Wiesener MS, Jurgensen JS, Rosenberger C, Scholze CK, Horstrup JH, Warnecke C et al. Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs. FASEB J 2003; 17: 271–273.
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