Ocular gene therapy trials due to report this year; Keeping an eye on clinical trials in 2008-Reference-Cited by-同舟云学术

Ocular gene therapy trials due to report this year; Keeping an eye on clinical trials in 2008

Published:2008-03-13 Issue:9 Volume:15 Page:633-634
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Bainbridge J W,Ali R R

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/gt200828.pdf

Reference5 articles.

1. Bainbridge JW, Tan MH, Ali RR . Gene therapy progress and prospects: the eye. Gene Therapy 2006; 13: 1191–1197.

2. Acland GM, Aguirre GD, Ray J, Zhang Q, Aleman TS, Cideciyan AV et al. Gene therapy restores vision in a canine model of childhood blindness. Nat Genet 2001; 28: 92–95.

3. Narfström K, Katz ML, Bragadottir R, Seeliger M, Boulanger A, Redmond TM et al. Functional and structural recovery of the retina after gene therapy in the RPE65 null mutation dog. Invest Ophthalmol Vis Sci 2003; 44: 1663–1672.

4. Acland GM, Aguirre GD, Bennett J, Aleman TS, Cideciyan AV, Bennicelli J et al. Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness. Mol Therapy 2005; 12: 1072–1082.

5. Le Meur G, Stieger K, Smith AJ, Weber M, Deschamps JY, Nivard D et al. Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium. Gene Therapy 2007; 14: 292–303.

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