Quantitative analysis of clinically relevant mutations occurring in lymphoid cells harboring γ-retrovirus-encoded hsvtk suicide genes-Reference-Cited by-同舟云学术

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Quantitative analysis of clinically relevant mutations occurring in lymphoid cells harboring γ-retrovirus-encoded hsvtk suicide genes

Published:2008-06-19 Issue:21 Volume:15 Page:1454-1459
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Wang X,Olszewska M,Capacio V,Stefanski J,Przybylowski M,Samakoglu S,Chang A H,Sadelain M,Rivière I

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/gt2008103.pdf

Reference29 articles.

1. Pathak VK, Temin HM . Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: deletions and deletions with insertions. Proc Natl Acad Sci USA 1990; 87: 6024–6028.

2. Pulsinelli GA, Temin HM . Characterization of large deletions occurring during a single round of retrovirus vector replication: novel deletion mechanism involving errors in strand transfer. J Virol 1991; 65: 4786–4797.

3. Roberts JD, Preston BD, Johnston LA, Soni A, Loeb LA, Kunkel TA . Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro. Mol Cell Biol 1989; 9: 469–476.

4. Varela-Echavarria A, Prorock CM, Ron Y, Dougherty JP . High rate of genetic rearrangement during replication of a Moloney murine leukemia virus-based vector. J Virol 1993; 67: 6357–6364.

5. Parthasarathi S, Varela-Echavarria A, Ron Y, Preston BD, Dougherty JP . Genetic rearrangements occurring during a single cycle of murine leukemia virus vector replication: characterization and implications. J Virol 1995; 69: 7991–8000.

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