Inhibition of autophagy with clarithromycin: a new strategy to enhance sensitivity of CML stem cells to tyrosine kinase inhibitors
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine
Link
http://www.nature.com/articles/leusup201225.pdf
Reference8 articles.
1. Vignir Helgason G, Karvela M, Holyoake TL . Kill one bird with two stones: potential efficacy of BCR-ABL and autophagy inhibition in CML. Blood 2011; 118: 2035–2043.
2. Bellodi C, Lidonnici MR, Hamilton A, Helgason GV, Soliera AR, Ronchetti M et al. Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells. J Clin Invest 2009; 119: 1109–1123.
3. Calabretta B, Salamoni P . Inhibition of autophagy: a new strategy to enhance sensitivity of chronic myeloid leukemia stem cells to tyrosine kinase inhibitors. Leuk Lymphoma 2011; 52 (Suppl 1): 54–59.
4. Jung CH, Ro SH, Cao J, Otto NM, Kim DH . mTOR regulation of autophagy. FEBS Lett 2010; 584: 1287–1295.
5. Nakamura M, Kikukawa Y, Takeya M, Mitsuva H, Hata H . Clarithromycin attenuates autophagy in myeloma cells. Int J Oncol 2010; 37: 815–820.
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