The DNA-binding domain mediates both nuclear and cytosolic functions of p53-Reference-Cited by-同舟云学术

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The DNA-binding domain mediates both nuclear and cytosolic functions of p53

Published:2014-05-11 Issue:6 Volume:21 Page:535-543
ISSN:1545-9993
Container-title:Nature Structural & Molecular Biology
language:en
Short-container-title:Nat Struct Mol Biol

Author:

Follis Ariele Viacava,Llambi Fabien,Ou Li,Baran Katherine,Green Douglas R,Kriwacki Richard W

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Link

http://www.nature.com/articles/nsmb.2829.pdf

Reference64 articles.

1. Green, D.R. & Kroemer, G. Cytoplasmic functions of the tumour suppressor p53. Nature 458, 1127–1130 (2009).

2. Chipuk, J.E. et al. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303, 1010–1014 (2004).

3. Leu, J.I., Dumont, P., Hafey, M., Murphy, M.E. & George, D.L. Mitochondrial p53 activates Bak and causes disruption of a Bak–Mcl1 complex. Nat. Cell Biol. 6, 443–450 (2004).

4. Chipuk, J.E., Bouchier-Hayes, L., Kuwana, T., Newmeyer, D.D. & Green, D.R. PUMA couples the nuclear and cytoplasmic proapoptotic function of p53. Science 309, 1732–1735 (2005).

5. Sattler, M. et al. Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis. Science 275, 983–986 (1997).

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