MEK inhibitors: a new class of chemotherapeutic agents with ocular toxicity
Author:
Publisher
Springer Science and Business Media LLC
Subject
Ophthalmology
Link
http://www.nature.com/articles/eye2015243.pdf
Reference4 articles.
1. Duncan KE, Chang LY, Patronas M . MEK inhibitors: a new class of chemotherapeutic agents with ocular toxicity. Eye 2015; 29: 1003–1012.
2. Martinez-Garcia M, Banerji U, Albanell J, Bahleda R, Dolly S, Kraeber-Bodéré F et al. First-in-human, phase I dose-escalation study of the safety, pharmacokinetics, and pharmacodynamics of RO5126766, a first-in-class dual MEK/RAF inhibitor in patients with solid tumors. Clin Cancer Res 2012; 18 (17): 4806–4819.
3. Zhao Y, Adjei AA . The clinical development of MEK inhibitors. Nat Rev Clin Oncol 2014; 11 (7): 385–400.
4. Wang D, Boerner SA, Winkler JD, LoRusso PM . Clinical experience of MEK inhibitors in cancer therapy. Biochim Biophys Acta 2007; 1773 (8): 1248–1255.
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