Alternative-splicing forms of the major phase II conjugating UGT1A gene negatively regulate glucuronidation in human carcinoma cell lines
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,Genetics,Molecular Medicine
Link
http://www.nature.com/articles/tpj200964.pdf
Reference29 articles.
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2. Ritter JK, Chen F, Sheen YY, Tran HM, Kimura S, Yeatman MT et al. A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini. J Biol Chem 1992; 267: 3257–3261.
3. Gong QH, Cho JW, Huang T, Potter C, Gholami N, Basu NK et al. Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus. Pharmacogenetics 2001; 11: 357–368.
4. Nagar S, Remmel RP . Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer. Oncogene 2006; 25: 1659–1672.
5. Guillemette C . Pharmacogenomics of human UDP-glucuronosyltransferase enzymes. Pharmacogenomics J 2003; 3: 136–158.
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