Allele-specific expression and gene methylation in the control of CYP1A2 mRNA level in human livers

Author:

Ghotbi Roza,Gomez Alvin,Milani Lili,Tybring Gunnel,Syvänen Ann-Christine,Bertilsson Leif,Ingelman-Sundberg Magnus,Aklillu Eleni

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,Genetics,Molecular Medicine

Reference49 articles.

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2. Bertilsson L, Carrillo JA, Dahl ML, Llerena A, Alm C, Bondesson U et al. Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test. Br J Clin Pharmacol 1994; 38: 471–473.

3. Tassaneeyakul W, Birkett DJ, Veronese ME, McManus ME, Tukey RH, Quattrochi LC et al. Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2. J Pharmacol Exp Ther 1993; 265: 401–407.

4. Kroemer HK, Gautier JC, Beaune P, Henderson C, Wolf CR, Eichelbaum M . Identification of P450 enzymes involved in metabolism of verapamil in humans. Naunyn Schmiedebergs Arch Pharmacol 1993; 348: 332–337.

5. Hartter S, Ursing C, Morita S, Tybring G, von Bahr C, Christensen M et al. Orally given melatonin may serve as a probe drug for cytochrome P450 1A2 activity in vivo: a pilot study. Clin Pharmacol Ther 2001; 70: 10–16.

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