Transcriptional programmes underlying cellular identity and microbial responsiveness in the intestinal epithelium
Author:
Publisher
Springer Science and Business Media LLC
Subject
Gastroenterology,Hepatology
Link
https://www.nature.com/articles/s41575-020-00357-6.pdf
Reference222 articles.
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2. Moor, A. E. et al. Spatial reconstruction of single enterocytes uncovers broad zonation along the intestinal villus axis. Cell 175, 1156–1167.e15 (2018). This paper reconstructs the pattern of gene expression along the crypt–villus axis using scRNA-seq with unprecedented resolution.
3. Larsson, E. et al. Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88. Gut 61, 1124–1131 (2012).
4. El Aidy, S. et al. Temporal and spatial interplay of microbiota and intestinal mucosa drive establishment of immune homeostasis in conventionalized mice. Mucosal Immunol 5, 567–579 (2012). This paper highlights the temporal and spatial dynamics of genome-wide gene expression in the intestine following microbiota colonization of germ-free mice.
5. Smale, S. T. Selective transcription in response to an inflammatory stimulus. Cell 140, 833–844 (2010).
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