High-Performance Digital Image Analyzer for Quantitative Autoradiography-Reference-Cited by-同舟云学术

High-Performance Digital Image Analyzer for Quantitative Autoradiography

Published:1986-10 Issue:5 Volume:6 Page:625-629
ISSN:0271-678X
Container-title:Journal of Cerebral Blood Flow & Metabolism
language:en
Short-container-title:J Cereb Blood Flow Metab

Author:

Lear James L.¹²,Mido Kenneth³,Plotnick Jeffrey²,Muth Russell²

Affiliation:

1. Nuclear Medicine, VA Medical Center, Palo Alto

2. Imagitronics, Ltd., Santa Clara, California, U.S.A.

3. Department of Radiology, Stanford University Medical Center, Stanford

Abstract

A digital image-processing system was developed for high–spatial resolution analysis of autoradiograms. The system uses a linear array of charge-coupled devices operating under computer control to scan and digitize autoradiograms into 512 × 512 matrices with 256 gray levels. Software was developed to facilitate quantitative analysis of autoradiograms produced in single- and multiple-tracer studies. Because of the high output, linearity, and accuracy of the solid-state detectors, the system was found to digitize autoradiograms significantly more precisely and accurately than previously described video camera- or photomultiplier tube-based scanning densitometers.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine,Neurology (clinical),Neurology

Link

http://journals.sagepub.com/doi/pdf/10.1038/jcbfm.1986.110

Reference17 articles.

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