Silibinin inhibits prostate cancer invasion, motility and migration by suppressing vimentin and MMP-2 expression

Author:

Wu Kai-jie,Zeng Jin,Zhu Guo-dong,Zhang Lin-lin,Zhang Dong,Li Lei,Fan Jin-hai,Wang Xin-yang,He Da-lin

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference26 articles.

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2. Feldman BJ, Feldman D . The development of androgen-independent prostate cancer. Nat Rev Cancer 2001; 1: 34–45.

3. Surh YJ . Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 2003; 3: 768–80.

4. Singh RP, Agarwal R . Prostate cancer prevention by Silibinin. Curr Cancer Drug Targets 2004; 4: 1–11.

5. Tyagi A, Agarwal C, Agarwal R . Inhibition of retinoblastoma protein (Rb) phosphorylation at serine sites and an increase in Rb-E2F complex formation by silibinin in androgen-dependent human prostate carcinoma LNCaP cells: role in prostate cancer prevention. Mol Cancer Ther 2002; 1: 525–32.

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