Adenovirus Expressing Both Thymidine Kinase and Soluble PD1 Enhances Antitumor Immunity by Strengthening CD8 T-cell Response

Author:

Shin Seung-Pil,Seo Hye-Hyun,Shin Jae-Hun,Park Hyung-Bae,Lim Dong-Pyo,Eom Hyeon-Seok,Bae Yong-Soo,Kim In-Hoo,Choi Kyungho,Lee Sang-Jin

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference44 articles.

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2. Antitumor effects of systemically delivered adenovirus harboring trans-splicing ribozyme in intrahepatic colon cancer mouse model;Jeong;Clin Cancer Res,2008

3. Cell cycle control pathways act as conditioning factors for TK/GCV sensitivity in pancreatic cancer cells;Abate-Daga;Biochim Biophys Acta,2010

4. Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo;Chen;Proc Natl Acad Sci USA,1994

5. Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: an effective in vitro drug sensitization system;Smythe;Cancer Res,1994

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