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Lens Epithelium-derived Growth Factor/p75 Qualifies as a Target for HIV Gene Therapy in the NSG Mouse Model

  • Published:2012-05 Issue:5 Volume:20 Page:908-917
  • ISSN:1525-0016
  • Container-title:Molecular Therapy
  • language:en
  • Short-container-title:Molecular Therapy

Author:

Vets Sofie,Kimpel Janine,Volk Andreas,De Rijck Jan,Schrijvers Rik,Verbinnen Bert,Maes Wim,Von Laer Dorothee,Debyser Zeger,Gijsbers Rik

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference49 articles.

1. Cellular co-factors of HIV-1 integration;Van Maele;Trends Biochem Sci,2006

2. Cellular cofactors involved in HIV assembly and budding;Spearman;Curr Opin HIV AIDS,2006

3. HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells;Cherepanov;J Biol Chem,2003

4. Virological and cellular roles of the transcriptional coactivator LEDGF/p75;Llano;Curr Top Microbiol Immunol,2009

5. The transcriptional co-activator LEDGF/p75 displays a dynamic scan-and-lock mechanism for chromatin tethering;Hendrix;Nucleic Acids Res,2011
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